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By Wolfgang Maret,Anthony Wedd,Robert JP Williams,Blanca Barquera,Jacqui Gulbis,Andrea Romani,James Cowan,Eugenio Garribba,Peter Lay,Gunter Schwarz,Michael Aschner,Paul Sharp,Pierre Cornelis,Richard Cammack,Elizabeth Theil,Peter Chivers,Giovanni Natille,Nick

Metal ions play key roles in biology. Many are crucial for catalysis, for electron move and for the fixation, sensing, and metabolism of gases. Others compete with these crucial steel ions or have poisonous or pharmacological effects.


This publication is based round the periodic desk and makes a speciality of the regulate of steel ions in cells. It addresses the molecular features of binding, shipping and garage that be sure balanced degrees of the fundamental components. Organisms have additionally constructed mechanisms to accommodate the non-essential steel ions. although, via new makes use of and production methods, organisms are more and more uncovered to altering degrees of either crucial and non-essential ions in new chemical kinds. they won't have built defenses opposed to a few of these kinds (such as nanoparticles).


Many illnesses akin to melanoma, diabetes and neurodegeneration are linked to steel ion imbalance. there is a deficiency of the basic metals, overload of both crucial or non-essential metals or perturbation of the general normal balance.


This e-book is the 1st to comprehensively survey the molecular nature of the final average stability of steel ions in foodstuff, toxicology and pharmacology. it truly is written as an creation to analyze for college kids and researchers in academia and and starts off with a bankruptcy by way of Professor R J P Williams FRS.

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Binding, Transport and Storage of Metal Ions in Biological Cells (Metallobiology) by Wolfgang Maret,Anthony Wedd,Robert JP Williams,Blanca Barquera,Jacqui Gulbis,Andrea Romani,James Cowan,Eugenio Garribba,Peter Lay,Gunter Schwarz,Michael Aschner,Paul Sharp,Pierre Cornelis,Richard Cammack,Elizabeth Theil,Peter Chivers,Giovanni Natille,Nick


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